US Open: Gauff vs. Vekic – Second Round Prediction, Odds & Analysis

Coco Gauff faced a tough first round at the US Open, but she’s moving on! Now, she’s set to clash with Donna Vekic in a highly anticipated second-round match. Will Gauff continue her strong run, or will Vekic pull off an upset? Don’t miss our full analysis and prediction!

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The US Open second round is set to deliver an electrifying clash as American tennis sensation Coco Gauff prepares to face off against the formidable Donna Vekic, a match anticipated to be filled with strategic rallies and intense competition. This deep dive offers a comprehensive tennis prediction and a detailed look at the US Open betting odds for what promises to be one of the most compelling fixtures of the tournament’s early stages.

Gauff, who has demonstrated her prowess on the Grand Slam stage, navigated a challenging first-round encounter, ultimately securing her passage in three hard-fought sets. Despite moments of vulnerability, including dropping the second set in a tiebreaker, her resilience shone through, underlining her determination to make another deep run at Flushing Meadows, a venue where she famously triumphed in 2023.

On the other side of the net, Donna Vekic also required three sets to advance, showcasing her own fighting spirit. Vekic is no stranger to success at the US Open, having reached the fourth round last year and the quarterfinals in 2019. Her prior experience and success on these courts make her a dangerous opponent, capable of challenging top-ranked players.

The history between Coco Gauff and Donna Vekic adds another layer of intrigue to this encounter. While Gauff secured a straight-sets victory against Vekic at the United Cup in Australia earlier in 2025, Vekic holds a notable win over the American from 2024, demonstrating her ability to overcome Gauff on the big stage. Their recent matchups suggest this will be anything but a straightforward affair.

Analyzing the current tennis betting landscape, Gauff enters this match as the favored player, with DraftKings indicating an implied probability of 88.24 percent for her to progress. However, the close nature of their previous encounters and both players’ challenging first rounds suggest that this match might not be as one-sided as the odds initially imply, inviting keen interest from bettors.

Both athletes showed signs of early tournament jitters in their respective opening matches. Vekic started slowly, while Gauff was pushed to her limits, particularly in the final two sets of her first-round match. These initial struggles highlight potential areas that either player could exploit or improve upon as they prepare for their high-stakes second-round battle in the US Open.

Considering the recent form, head-to-head history, and the pressure of a Grand Slam event, predicting the exact outcome remains challenging. While Gauff’s higher ranking and recent form might give her an edge, Vekic’s proven ability to perform well at the US Open and her past victory against Gauff mean this match is poised to be a captivating contest. Fans can anticipate a thrilling display of athleticism and strategic play under the Thursday night lights.

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